Fully integrate research, development, and biomanufacturing
Novel treatments with novel data challenges
Fueled by recent scientific milestones, cell and gene therapies (CGTs) have emerged as one of the most promising fields in human health. Drug hunters today have a new, exquisite understanding of human biology and the technological advancements necessary to make novel therapeutics. These new treatments are bringing hope to patients — and complexity to how labs operate and manage scientific data.
Cell and gene companies face novel challenges that have redefined—and in some cases completely reinvented—drug design, development, and manufacturing workflows.
Companies working on cell and gene therapies need a solution to manage all their data—and make R&D and manufacturing faster, easier, and cheaper than ever before. Unfortunately, existing solutions are not well-suited to the biological complexity and unique R&D/manufacturing dynamic of cell and gene therapies.
Inherently complex therapeutics Gene therapies involve assembling sophisticated payloads that can be delivered to precise targets and manipulate gene expression in a desirable way. Cell therapies meanwhile involve working with living and functional cells. Both have forced biotechs to adapt their processes and adopt new tech stacks.
Blurred lines between R&D and manufacturingCGT product development requires a tight integration between protocols and knowledge developed in the lab, and their smooth roll-out into compliant production. R&D equipment such as flow cytometers often needs to be repurposed for production workflows, despite a lack of industry roadmaps to follow.
Demanding production processesUnlike with traditional drugs, the process itself is often the IP with CGTs. Highly specialized workflows that maintain a high level of quality of the therapeutic end-products and keep costs of goods and services (COGS) under control are a critical challenge.
Reliance on collaboration and CDMOs The complexity of CGT workflows, and the specialized training and equipment involved, mean that biotechs and biopharma have become increasingly dependent on partnerships with research hospitals and with CDMOs to bring these treatments from bench to bedside.
Your lab on Ganymede - Flow Cytometry
Cell and gene therapy companies operate in an area of tremendous biological complexity. In creating new therapeutics, they also create novel workflows for R&D and manufacturing.
Ganymede’s Lab-as-Code platform was specifically designed to help labs with complex biological data and processes. We give labs a birds’ eye view of their entire lab’s activities and empower them to make data-driven, informed decisions that fuels them from early R&D, through clinical trials, to manufacturing.
What’s the most common instrument cell and gene companies struggle with? We see it with our clients all the time — flow cytometers.
Flow cytometers—they’re a workhorse instrument in any lab working with cells, starting from early stage R&D through biomanufacturing.
For gene therapies, this may be validation of the delivery and outcome of a potential treatment. For cell therapies, this might be checking your engineered cells for quality and function. Either way, you’ll likely run into these “clogs” in your flow cytometry workflows:
Ganymede centralizes all your flow cytometer data in the cloud, alongside all your lab’s data from every other source. It’s all automatically formatted and cleaned, and it can be analyzed directly in the cloud. Now your scientist’s process looks more like this: run experiment, open workspace, start analyzing.
When Ganymede is powering your flow cytometry data infrastructure:
Resources to Explore
Our co-founder Nathan Clark discusses modern labs on Qualio's From Lab to Launch podcast.
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